
At Avena Natural Health, we hold a deep respect for how our bodies signal balance—and when that balance slips, we look to real, thoughtful interventions. somatostatin peptide therapy harnesses synthetic versions of the body’s own inhibitory hormone, somatostatin. These analogs—octreotide, lanreotide, pasireotide—mimic the natural hormone while lasting far longer, creating a focused, sustained way to calm hormonal imbalances while supporting root-cause healing.
How Octreotide, Lanreotide, Pasireotide Work in Practice
Octreotide jumps in as a robust stand-in for somatostatin, curbing the release of key hormones—growth hormone, glucagon, insulin—with targeted precision. Lanreotide comes in as its long-acting sibling, riding on the same biological logic but with a gentler, slower-release rhythm, making it ideal for ongoing management. Pasireotide takes it a step further—it binds multiple receptor subtypes with higher affinity, especially subtype 5, offering hope when first-generation analogs don’t quite get the job done.
When First-Generation Analogs Aren’t Enough: Somatostatin Peptide Therapy Steps In
In cases like acromegaly or resistant pituitary tumors, patients sometimes need a backup plan. Here, somatostatin peptide therapy shines when octreotide or lanreotide leave gaps. Pasireotide can outperform those drugs when hormone levels remain stubbornly elevated, stepping in with broader receptor targeting and improved outcomes.
A Compassionate Approach at Avena Natural Health
Our team knows that every experience with hormonal imbalance carries weight beyond the hormones themselves. We approach each story with empathy, weaving in supportive layers like gentle nutrition, stress regulation, lifestyle guidance, and sometimes mild hyperbaric oxygen therapy when circulation or tissue health needs a boost. We never treat labs in isolation; we’re treating lives, with care.

Addressing Root Causes, Not Just Symptoms
Somatostatin analogs offer precision, but we always ask: what’s feeding the imbalance? We explore foundational shifts—nutrition, stress response, sleep quality, metabolism, emotional life—and when warranted, pair peptide therapy with individual plans. Occasionally, patients also benefit from peptide therapy in San Diego combined with lifestyle supports that flow together, not as scattered add-ons, but as parts of a cohesive whole.
When Hormonal Weight Gain Becomes a Concern
Hormonal weight gain can feel baffling—and frustrating. In thoughtful hands, it’s not about blaming metabolism but understanding signals. Here, treatment for hormonal weight gain may include gentle hormone modulation, peptide support, thyroid balancing, and movement practices that feel human, not punitive. We believe change works best when it’s rooted in compassion and lived step by step.
Looking at the Big Picture of Somatostatin Peptide Therapy
At Avena Natural Health, we’ve seen that somatostatin analogs are safe and effective when monitored. Octreotide and lanreotide control hormone levels and shrink some tumors. Pasireotide offers broader effectiveness but comes with a need for close watch over blood sugar—it can nudge glucose up, so gentle support and monitoring matter. From gallbladder awareness to digestion shifts, it’s our job to stay proactive and responsive, day to day, alongside you.
Natural Supports and Future Horizons
Amid all this, some people dream of a natural type 1 diabetes treatment—we get it. While somatostatin analogs aren’t that, they can help regulate hormones and blood sugar. Coupled with real-food nutrition, body-respecting movement, and stress-soothing tools, they create a climate where your body can find better balance. We’re not offering a fantasy cure. We’re offering grounded science and wholehearted support toward better stability.
If hormonal symptoms are wearing you down, yet you don’t want to be boxed into a narrow medical path, we’re here. At Avena Natural Health, we believe in modern peptide tools gently guided by real-person care. Every hormone tells a story, and we’re here to help rewrite that story together—healing, not just treating, in a way that feels like you.
Media Credit: All photos licensed from Adobe.
Frequently Asked Questions
What is somatostatin peptide therapy and who is it for?
It’s a way to use lab-made versions of somatostatin—like octreotide, lanreotide, pasireotide—to gently dial back hormone overproduction, especially when surgery isn’t an option or symptoms linger.
How do these analogs differ?
Octreotide acts swiftly and is shorter-acting. Lanreotide delivers a smoother, long-acting release. Pasireotide targets more receptor types and can be used when others fall short, though it may affect blood sugar more.
What should I expect on peptide therapy?
It’s not a switch you flip once—you’ll meet frequently with our team to monitor hormone levels, glucose, digestion, and overall energy. Side effects like mild digestive shifts, gallbladder effects, or sugar changes are possible, so we stay vigilant.
Can this therapy stand alone?
Not at Avena. We weave in holistic care. Somatostatin analogs work better when paired with natural supports, personalized plans, stress care, and whole-body respect.
Is this just for rare disorders?
Not always. While these analogs are approved for conditions like acromegaly or neuroendocrine tumors, they can also help with other hormonal imbalances under careful, individualized guidance.

Dr. Laura Kostrzewski, a San Diego native, completed her undergraduate degree at California Polytechnic State University, earning a BS in animal science with minors in Spanish and Psychology. She then earned her Multiple Subject Teaching Credential and taught fifth grade in the central coast of California for two years. After being extremely involved in her grandfather’s journey with Parkinson’s disease and end-of-life care, Dr. Kostrzewski decided to move back to San Diego and enroll at Bastyr University California. Dr. Kostrzewski received her doctorate in Naturopathic Medicine from Bastyr University California in June of 2019, and then went on to complete her residency at Bastyr. Before AVENA Wellness, DR. K started her own private practice, focusing on management of neurodegenerative conditions, and continued teaching at Bastyr as adjunct faculty, until founding Avena Health.